Although the first description of the anatomy of brain lymphatics dates back 250 years, it is only in the past decade or so that there is groundbreaking evidence from both animal and human studies proving the existence of a brain clearance system via CSF and ISF flow. This shows that fundamental elements of the brain anatomy and physiology have been neglected for too long and that there is an urgent need for in vivo imaging technology to monitor brain clearance. It is only in the recent past that some elements of brain clearance are being imaged using cutting-edge MR techniques such as contrast-enhanced MRI, diffusion tensor imaging, perfusion-weighted imaging, MR elastography, and flow studies to name a few. There is tremendous excitement in this field and such discoveries have the potential to revolutionize our understanding of most neurodegenerative and neuroinflammatory diseases.The workshop will have a strong multi-disciplinary character and attendees will get ample chances to share their knowledge, speak to experts and peers, and develop joint projects. We will also suggest protocols, spend time using selected software, and invite proffered full papers on this field.

Organizers: N. Agarwal, O. Baledent, L. Hirschler, M.J.P. van Osch

21-24 September 2022 Rome, Italy